Description
Product Characteristics: Protein E6 is a transcriptional transactivator. Protein E6 binds double stranded DNA by similarity. Protein E6 is localized in host nucleus matrix. It belongs to the papillomaviridae E6 protein family.
Target Information: Plays a major role in the induction and maintenance of cellular transformation. E6 associates with host UBE3A/E6-AP ubiquitin-protein ligase and modulates its activity. Protects host keratinocytes from apoptosis by mediating the degradation of host BAK1. May also inhibit host immune response. {ECO:0000255:HAMAP- Rule:MF_04006}